These hotels are fantastic!
Maison Mochino, located in the center of Milan, has incredibly unique rooms:
Hotel des arts, in our very own San Francisco. Keep in mind, the site is a little shoty, but the rooms look incredible. The hotel even boasts work by the local artist Chor Boogie. Funky name, but great work.
By far my favorite hotel, is the Ice Hotel located just across the pond, in Sweden. I would LOVE to visit this place! It is quite a process to create this hotel, as the entire building melts every year and has to be rebuilt. What an opportunity to experiment with new architectural designs.